of: SIC
E 'known as Lox1 , and is a enzyme that can become an important ally of drugs against cancer , making them even more effective than current ones. Secure it, scientists from the Institute of Cancer Research, or the British Institute for research on cancer , managed to stop the mice metastasis from a tumor to breast to other organs. According to a team led by Janine Erler, these results have revealed a new "target fantastic drug" targeted and will soon be used clinically.
To understand the possible impact of this result, considering that 90% of cancer deaths is caused by metastasis of cancer . Patients suffering from breast cancer in the study had high levels of ' Loxl2 enzyme, which was particularly important in the early stages of disease, because it helps cancer cells to escape from breast tissue to enter the bloodstream. In the case of breast cancer, scientists have shown that high levels of enzyme Loxl2 were connected with the spread of cancer and low survival rates.
In their study on mice, researchers have used chemical compounds and antibodies to block the activity: in this way were able to halt the spread of cancer other tissues. "These findings are important not only for drug development, but also to develop predictive tests on the possibility of cancer metastasis in the patient," said Janine Erler.
To understand the possible impact of this result, considering that 90% of cancer deaths is caused by metastasis of cancer . Patients suffering from breast cancer in the study had high levels of ' Loxl2 enzyme, which was particularly important in the early stages of disease, because it helps cancer cells to escape from breast tissue to enter the bloodstream. In the case of breast cancer, scientists have shown that high levels of enzyme Loxl2 were connected with the spread of cancer and low survival rates.
In their study on mice, researchers have used chemical compounds and antibodies to block the activity: in this way were able to halt the spread of cancer other tissues. "These findings are important not only for drug development, but also to develop predictive tests on the possibility of cancer metastasis in the patient," said Janine Erler.
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